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New targets on the KRAS pathway
Frank McCormick
UCSF Helen Diller Family Comp. Cancer Ctr., San Francisco, CA, United States
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Chairperson
Lucy A Godley
Univ. of Chicago, Chicago, IL, United States
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Histone profiling by ChIP-sequencing and mass spectrometry: methods and applications
Kathrin Maria Bernt
The Center for Cancer and Blood Disorders, Denver, CO, United States
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Methods to distinguish 5-methylcytosine from 5-hydroxymethylcytosine
Lucy A Godley
Univ. of Chicago, Chicago, IL, United States
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Next-generation sequencing-based methods for the study of cytosine modifications in primary leukemia specimens
Maria Eugenia Figueroa
U. of Michigan, Ann Arbor, MI, United States
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Computational analysis of whole genome bisulfite sequencing data
Wei Li
Baylor College of Medicine Cancer Ctr., Houston, TX, United States
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Introduction
Mario Sznol
Yale Cancer Ctr., New Haven, CT, United States
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Targeting checkpoint receptors: Beyond CTLA-4 and PD-1
Ana C. Anderson
Harvard Medical School/Brigham & Women's Hospital, Boston, MA, United States
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Targeting the B7-H family and BTLA inhibitory receptors for cancer treatment
Drew M. Pardoll
Johns Hopkins Kimmel Comp. Cancer Ctr., Baltimore, MD, United States
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Harnessing the power of TNF-receptor family members to enhance immune-mediated rejection of tumors
Andrew D Weinberg
Robert W. Franz Cancer Research Center, Portland, OR, United States
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Oncogenic alterations of metabolism
Chi Van Dang
Abramson Cancer Ctr. of Univ. of Penn., Philadelphia, PA, United States
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How cancer powers biosynthesis and redox defense
Joshua D Rabinowitz
Princeton Univ., Princeton, NJ, United States
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Role of altered metabolism in cancer
Matthew G. Vander Heiden
MIT Koch Inst. for Integrated Cancer Res., Cambridge, MA, United States
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Stable isotope-resolved metabolomic (SIRM) approach: From bench to bedside
Teresa W. m. Fan
University of Kentucky, Lexington, KY, United States
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Introduction to Workshop
Lee M. Ellis
UT MD Anderson Cancer Ctr., Houston, TX, United States
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Advancing through the phases of clinical trials (What is a phase I-III clinical trial, and what purposes do they serve)
S. Gail Eckhardt
Univ. of Colorado Cancer Ctr., Aurora, CO, United States
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How are clinical trials funded
Neal J. Meropol
University Hospitals Seidman Cancer Center & Case Western Reserve University, Cleveland, OH, United States
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What role does the FDA play in cancer clinical trials
Elizabeth M. Jaffee
Johns Hopkins Univ., Baltimore, MD, United States
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Standard and functional imaging and its role in determining endpoints in clinical trials (including modified RECIST criteria for biologics)
Richard L. Wahl
Johns Hopkins Univ. School of Medicine, Baltimore, MD, United States
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CDK4/6 inhibition: Cellular outcomes, synthetic lethal interactions with oncogene activation and clinical development of selective compounds
Geoffrey I. Shapiro
Dana-Farber Cancer Inst., Boston, MA, United States
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Cyclin E-amplified ovarian cancer: Tumor biology and treatment strategies
David D L Bowtell
Peter MacCallum Cancer Ctr., E. Melbourne, Australia
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Drugging the cell cycle checkpoint regulator Chk1
Alan Eastman
Norris Cotton Cancer Ctr., Lebanon, NH, United States
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Cdc20 as a novel therapeutic target for cancer treatment
Wenyi Wei
Beth Israel Deaconess Medical Ctr., Boston, MA, United States
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Cancer evolution at single-cell genomic resolution
Nicholas E. Navin
UT MD Anderson Cancer Ctr., Houston, TX, United States
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Experimental and mathematical approaches to dissect breast tumor evolution
Kornelia Polyak
Dana-Farber Cancer Inst., Boston, MA, United States