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How single-cell genomics is revolutionizing cancer research
Nicholas E. Navin
UT MD Anderson Cancer Ctr., Bellaire, TX, United States
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Deciphering selection in lung cancer evolution
Thomas Watkins
The Francis Crick Institute, London, United Kingdom
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Insights into cancer evolution and selection from whole genome sequencing studies?
Peter J. Campbell
Wellcome Trust Sanger Inst., Cambridge, United Kingdom
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Advances in analytical methods for clonal evolution inference at single-cell and bulk resolution
Sohrab Shah
BC Cancer Agency Vancouver Ctr., Vancouver, BC, Canada
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The broad cell line factory: Developing early passage cell lines for cancer biology and drug development
Jesse S. Boehm
Broad Institute, Cambridge, MA, United States
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Utility of patient-derived xenograft models to mirror precision oncology clinical trials
James H. Doroshow
NCI-DCTD, Bethesda, MD, United States
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- Some slides withheld
Pharmacodynamic modeling to predict biologically effective drug dosing
Ralph E. Parchment
Frederick National Laboratory/SAIC-Frederick, Inc., Frederick, MD, United States
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- Some slides withheld
Spontaneous canine malignancies: Models for precision cancer medicine
Amy K Leblanc
National Cancer Institute, Bethesda, MD, United States
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Design and outcome data from molecularly-targeted basket trials
Edith A. Perez
Genentech, Inc., South San Francisco, CA, United States
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How NCI collaborates with Pharma and Academic Investigators: Clinical Development Plan for Osimertinib as a Case Study
Jeffrey A. Moscow
National Cancer Institute, Bethesda, MD, United States
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- Some slides withheld
Update of biomarker prevalence identified by next generation sequencing
Siraj M Ali
Foundation Medicine, Cambridge, MA, United States
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Novel clinical trial designs for targeted agents
Mithat Gonen
Mem. Sloan Kettering Cancer Ctr., New York, NY, United States
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Illuminating the tumor microenvironment using single and multiplex immunohistochemistry
Janis Marie Taube
Johns Hopkins Univ. School of Medicine, Baltimore, MD, United States
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Next-generation pathology: Quantitative immunofluorescence and imaging mass cytometry
Kurt Alex Schalper
Yale Univ., New Haven, CT, United States
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Tissue-based genomic biomarkers for immunotherapy
Matthew David Hellmann
Mem. Sloan Kettering Cancer Ctr., New York, NY, United States
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The MANA functional expansion of specific T cells (MANAFEST) assay: A sensitive molecular approach for clinical monitoring of peripheral anti-tumor immunity
Kellie N Smith
Johns Hopkins Univ. School of Medicine, Baltimore, MD, United States
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Gene dysregulation in cancer: The view from chromosome neighborhoods
Richard A. Young
MIT Whitehead Inst. for Biomed. Research, Cambridge, MA, United States
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Histone modifications and gene expression in cancer
Scott A. Armstrong
Dana-Farber Cancer Institute, Boston, MA, United States
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ATP-dependent chromatin remodeling complexes in human cancer
Cigall Kadoch
Dana-Farber Cancer Inst., Boston, MA, United States
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Enhancer reprogramming during cancer progression
Christopher R. Vakoc
Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, United States
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Lessons and opportunities for probe development in cancer research
David E. Uehling
Ontario Inst. for Cancer Research, Toronto, ON, Canada
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Value proposition of chemical probes in the development of translational phenotypic bioassays towards target discovery and validation
Ivan Cornella-Taracido
Merck & Co., Boston, MA, United States
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Chemical probes of chromatin regulation: Case histories
Stephen V. Frye
Univ. of North Carolina at Chapel Hill, Chapel Hill, NC, United States
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Mechanism and therapeutic application of RNA-guided immune systems
Christof Fellmann
UC Berkeley, Berkeley, CA, United States
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Retooling CRISPR to turn genes on and off
Luke A. Gilbert
UCSF, San Francisco, CA, United States