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Phase I Studies of Immune-Based Therapies and a Novel RNAi Agent
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A phase I study of MPDL3280A, an engineered PD-L1 antibody in patients with locally advanced or metastatic tumors
Michael S Gordon
Premiere Oncology of Arizona, Scottsdale, AZ, United States
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Antoni Ribas
UCLA Medical Ctr., Los Angeles, CA, United States
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A phase I dose escalation study of TKM-080301, a RNAi therapeutic directed against PLK1, in patients with advanced solid tumors
Ramesh K Ramanathan
Virginia G. Piper Cancer Center/TGen, Scottsdale, AZ, United States
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Josep Tabernero
Vall d'Hebron University Hospital, Barcelona, Spain
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Targeting MUC16 with the antibody-drug conjugate (ADC) DMUC5754A in patients with platinum-resistant ovarian cancer: A phase I study of safety and pharmacokinetics
Joyce Liu
Harvard Medical School, Boston, MA, United States
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First-in-human phase I dose escalation study of a novel anti-mesothelin antibody drug conjugate (ADC), BAY 94-9343, in patients with advanced solid tumors
Johanna Bendell
Sarah Cannon Research Institute, Nashville, TN, United States
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Mitchell Ho
National Cancer Inst., Bethesda, MD, United States

