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New Treatment Approaches for Breast and Ovarian Cancer
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A phase Ib study of miransertib (ARQ 092) in combination with anastrozole in patients with PIK3CA or AKT1-mutant ER+ endometrial or ovarian cancer.
Vicky Makker
Mem. Sloan Kettering Cancer Ctr., New York, NY, United States
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Targeting MUC16 with the THIOMABTM-drug conjugate DMUC4064A in patients with platinum-resistant ovarian cancer: A phase I expansion study
Kathleen Moore
University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States
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Phase I safety, pharmacokinetic and pharmacodynamic study of CYC065, a cyclin dependent kinase inhibitor, in patients with advanced cancers (NCT02552953)
Khanh T Do
Dana-Farber Cancer Institute, Boston, MA, United States
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OlympiAD final overall survival: Olaparib versus chemotherapy treatment of physician's choice (TPC) in patients with HER2-negative metastatic breast cancer (mBC) and a germline BRCA mutation (gBRCAm)
Mark E Robson
Memorial Sloan Kettering Cancer Center, New York, NY, United States
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Cyclin E1 (CCNE1) expression associates with benefit from palbociclib in metastatic breast cancer (MBC) in the PALOMA3 trial
Nicholas C. Turner
Royal Marsden Hospital and Institute of Cancer Research, London, United Kingdom
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MONARCH 3: Abemaciclib as initial therapy for patients with HR+, HER2- advanced breast cancer - Results from the preplanned final PFS analysis
Matthew P Goetz
Mayo Clinic, Rochester, MN, United States
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Primary results from FAIRLANE (NCT02301988), a double-blind placebo (PBO)-controlled randomized phase II trial of neoadjuvant ipatasertib (IPAT) + paclitaxel (PAC) for early triple-negative breast cancer (eTNBC)
Mafalda Oliveira
Vall d'Hebron University Hospital, Vall d’Hebron Institute of Oncology (VHIO) and SOLTI Breast Cancer Research Group, Barcelona, Spain