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Biomarkers in Immuno-oncology
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Biomarker analyses from a phase I study of WNT974, a first-in-class Porcupine inhibitor, in patients (pts) with advanced solid tumors
Jordi Rodon
Vall d’Hebron University Hospital and Universitat Autònoma de Barcelona, Barcelona, Spain
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Effect of JAK/STAT or PI3Kδ plus PD-1 inhibition on the tumor microenvironment: Biomarker results from a phase Ib study in patients with advanced solid tumors
John M Kirkwood
UPMC Hillman Cancer Center Melanoma and Skin Cancer Program, Pittsburgh, PA, United States
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Epacadostat plus durvalumab in patients with advanced solid tumors: preliminary results of the ongoing, open-label, phase I/II ECHO-203 study
Aung Naing
The University of Texas MD Anderson Cancer Center, Houston, TX, United States
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Nivolumab monotherapy in patients with advanced platinum-resistant urothelial carcinoma: Efficacy and safety update and association between biomarkers and overall survival in CheckMate 275
Padmanee Sharma
UT MD Anderson Cancer Ctr., Houston, TX, United States
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Safety, efficacy, and immune correlates of alternative doses and schedules of entinostat combined with pembrolizumab in patients with advanced solid tumors - results from SNDX-275-0141 phase I trial
Anthony W. Tolcher
START, San Antonio, TX, United States
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Preliminary phase 1 profile of BMS-986179, an anti-CD73 antibody, in combination with nivolumab in patients with advanced solid tumors
Lillian L Siu
Princess Margaret Cancer Centre, University of Toronto, Toronto, ON, Canada
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Safety, activity, and biomarkers for neoadjuvant anti-PD-1 therapy in melanoma
Alexander C Huang
University Of Pennsylvania, Philadelphia, PA, United States
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The anti-PD-1 antibody spartalizumab (PDR001) in combination with dabrafenib and trametinib in previously untreated patients with advanced BRAF V600-mutant melanoma: First efficacy, safety, and biomarker findings from the part 2 biomarker cohort of COMBi-i
Reinhard Dummer
University Hospital Zürich, Zürich, Switzerland