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presentations: 1 to 25 of 10634
page: of 426 records per page:
Keynote Session
Therapeutic modulation of E3 ubiquitin ligase activity
Benjamin L. Ebert
Dana-Farber Cancer Institute, Boston, MA, United States
from 2019 Molecular Targets and Cancer Therapeutics conference on October 26, 2019 5:00 PM-7:00 PM
Plenary Session 3: Targeting DNA Repair, PARP, and Beyond
Navigating gene-gene and drug-gene interaction landscapes underpinning the DNA damage response
Daniel Durocher
Lunenfeld-Tanenbaum Research Institute, Toronto, ON, Canada
from 2019 Molecular Targets and Cancer Therapeutics conference on October 28, 2019 8:00 AM-9:45 AM
Plenary Session 4: The Role of Liquid Biopsies in Guiding Cancer Therapeutics-- Detection, Response Monitoring, and Resistance
Background and use of circulating tumor-derived DNA and circulating tumor cells as biomarkers
Martijn Lolkema
Erasmus MC, Rotterdam, Netherlands
from 2019 Molecular Targets and Cancer Therapeutics conference on October 28, 2019 10:00 AM-11:45 AM
Concurrent Session 5: Targeting the RAS/MAP Kinase Pathway
The KRASG12C inhibitor, MRTX849, provides insight toward therapeutic susceptibility of KRAS mutant cancers
James G Christensen
Mirati Therapeutics, San Diego, CA, United States
from 2019 Molecular Targets and Cancer Therapeutics conference on October 28, 2019 4:15 PM-6:00 PM
Concurrent Session 5: Targeting the RAS/MAP Kinase Pathway
A phase 1 clinical trial evaluating the pharmacokinetics (PK), safety, and clinical activity of MRTX849, a mutant-selective small molecule KRASG12C inhibitor, in advanced solid tumors
Pasi A Jänne
Dana-Farber Cancer Institute, Boston, MA, United States
from 2019 Molecular Targets and Cancer Therapeutics conference on October 28, 2019 4:15 PM-6:00 PM
Plenary Session 5: Immuno-Oncology
The dark side of immunotherapy
Emiliano Calvo
Start Madrid, Madrid, Spain
from 2019 Molecular Targets and Cancer Therapeutics conference on October 29, 2019 8:00 AM-9:45 AM
Plenary Session 6: Frontiers in Small Molecule Drug Discovery
Inhibitors of the HSF1 stress pathway derived from phenotypic screening: Targeting non-oncogene addiction in ovarian and other cancers
Paul Workman
The Institute of Cancer Research, London, United Kingdom
from 2019 Molecular Targets and Cancer Therapeutics conference on October 29, 2019 10:00 AM-11:45 AM
Concurrent Session 9: Emergent Themes from the Study of Resistance to Targeted Therapeutics
Early lessons from initial acquired resistance to TRK inhibitors
David M Hyman
Memorial Sloan Kettering Cancer Center, New York, NY, United States
from 2019 Molecular Targets and Cancer Therapeutics conference on October 29, 2019 4:15 PM-6:00 PM
Plenary Session 7: Big Data / Real-World Evidence
From big data to smart data: Overcoming biomedical reductionism
Sean Khozin
U.S. Food & Drug Administration, Silver Spring, MD, United States
from 2019 Molecular Targets and Cancer Therapeutics conference on October 30, 2019 8:00 AM-9:45 AM
Plenary Session 8: Rational Approaches to the Discovery and Testing of Combination Therapies
Identifying novel immunotherapy strategies using human samples and pre-clinical models
Jennifer L Guerriero
Dana-Farber Cancer Institute, Boston, MA, United States
from 2019 Molecular Targets and Cancer Therapeutics conference on October 30, 2019 10:00 AM-12:00 PM
Educational Session: Targeting Molecular Subtypes-- Successes and Failures
Successes and failures of targeted drug development in adult and pediatric sarcomas
Jaap Verweij
Erasmus University Medical Center, Rotterdam, Netherlands
  •  
  • Free
  • Coming soon
  • Some slides withheld
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from 2019 Molecular Targets and Cancer Therapeutics conference on October 26, 2019 3:00 PM-4:45 PM
Educational Session: Targeting Molecular Subtypes-- Successes and Failures
Successes and failures of targeted drug development in pediatric tumors
Elizabeth Fox
Children’s Hospital of Pennsylvania, Philadelphia, PA, United States
from 2019 Molecular Targets and Cancer Therapeutics conference on October 26, 2019 3:00 PM-4:45 PM
Educational Session: Targeting Molecular Subtypes-- Successes and Failures
Targeted therapy with protein kinase inhibitors: Lessons learned from the last 20 years
Michael C Heinrich
Oregon Health and Science University, Portland, OR, United States
from 2019 Molecular Targets and Cancer Therapeutics conference on October 26, 2019 3:00 PM-4:45 PM
Keynote Session
Dissecting antitumor immune response in ovarian cancer
George Coukos
University of Lausanne, Lausanne, Switzerland, Lausanne, Switzerland
from 2019 Molecular Targets and Cancer Therapeutics conference on October 26, 2019 5:00 PM-7:00 PM
Plenary Session 1: The Landscape of CAR-T Therapeutics
New CAR T cells on the horizon
Marcela V Maus
Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States
  •  
  • Permission not
    granted for presentation
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from 2019 Molecular Targets and Cancer Therapeutics conference on October 27, 2019 8:00 AM-9:45 AM
Plenary Session 1: The Landscape of CAR-T Therapeutics
New targets and technologies for CAR-T
Michael Hudecek
University Hospital Wurzburg, Wurzburg, Germany
  •  
  • Permission not
    granted for presentation
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from 2019 Molecular Targets and Cancer Therapeutics conference on October 27, 2019 8:00 AM-9:45 AM
Plenary Session 1: The Landscape of CAR-T Therapeutics
Engineering CAR T Cells to Overcome Resistance
Crystal L Mackall
Stanford University School of Medicine, Stanford, California, Stanford, CA, United States
from 2019 Molecular Targets and Cancer Therapeutics conference on October 27, 2019 8:00 AM-9:45 AM
Plenary Session 2: From Glues to ‘TACs-- Re-directing Cellular Protein Degradation
Targeted Protein Degradation as a new Approach to Cancer Drugs
Nathanael S Gray
Dana-Farber Cancer Institute, Boston, MA, United States
from 2019 Molecular Targets and Cancer Therapeutics conference on October 27, 2019 10:00 AM-11:45 AM
Plenary Session 2: From Glues to ‘TACs-- Re-directing Cellular Protein Degradation
Exploiting E3 ligases for target validation and drug discovery: What have we learnt so far?
Rajesh Chopra
The Institute of Cancer Research, London, United Kingdom
from 2019 Molecular Targets and Cancer Therapeutics conference on October 27, 2019 10:00 AM-11:45 AM
Plenary Session 2: From Glues to ‘TACs-- Re-directing Cellular Protein Degradation
The zinc-finger degrome
Nicolas H. Thoma
Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland
  •  
  • Free
  • Coming soon
  • Some slides withheld
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  •  
from 2019 Molecular Targets and Cancer Therapeutics conference on October 27, 2019 10:00 AM-11:45 AM
Spotlight on Proffered Papers 1
A phase I study targeting the APE1/Ref-1 DNA repair-redox signaling protein with the APX3330 inhibitor
Mark R. Kelley
Indiana University School of Medicine, Indianapolis, IN, United States
from 2019 Molecular Targets and Cancer Therapeutics conference on October 27, 2019 11:50 AM-12:20 PM
Spotlight on Proffered Papers 1
Clinical proof of concept for MCLA-128, a bispecific HER2/3 antibody therapy, in NRG1 fusion-positive cancers
Alison M Schram
Memorial Sloan Kettering Cancer Center, New York, NY, United States
from 2019 Molecular Targets and Cancer Therapeutics conference on October 27, 2019 11:50 AM-12:20 PM
Spotlight on Proffered Papers 1
A phase 1 trial of AG-270 in patients with advanced solid tumors or lymphoma with homozygous MTAP deletion
Rebecca S Heist
Massachusetts General Hospital, Boston, MA, United States
from 2019 Molecular Targets and Cancer Therapeutics conference on October 27, 2019 11:50 AM-12:20 PM
Concurrent Session 1: CAR-T and Directed T-cell Therapy-- Advancing Beyond B-ALL
CAR-T and directed T-cell therapy: Where are we right now?
Victor Moreno
START Madrid, Hospital Fundación Jiménez Díaz, Madrid, Spain
from 2019 Molecular Targets and Cancer Therapeutics conference on October 27, 2019 4:15 PM-6:00 PM
Concurrent Session 1: CAR-T and Directed T-cell Therapy-- Advancing Beyond B-ALL
T cell receptor gene therapy for a public neoantigen derived from mutated PIK3CA, a dominant driver oncogene in breast and endometrial cancers
Smita Chandran
Memorial Sloan Kettering Cancer Center, New York, NY, United States
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  • Permission not
    granted for presentation
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from 2019 Molecular Targets and Cancer Therapeutics conference on October 27, 2019 4:15 PM-6:00 PM
<< first | < prev next > | last >>
presentations: 1 to 25 of 10634
page: of 426 records per page: