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Turning the heat up on pancreatic cancer: Lessons on overcoming a “cold” immunologic microenvironment
Elizabeth M Jaffee
Johns Hopkins Sidney Kimmel Comp. Cancer Ctr., Baltimore, MD, United States
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Introduction
Lisa A Newman
Weill Cornell Medicine, New York, NY, United States
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Colorectal cancer in Nigeria: High tech and low-tech approaches to improving patient outcomes
Olusegun I Alatise
Obafemi Awolowo Univ., Ile-Ife, Osun, Nigeria
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Spliceomics: Alternative RNA splicing as a source of ancestry-related molecular targets in precision oncology and cancer disparities
Steven R Patierno
Duke Cancer Institute, Durham, NC, United States
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The DARC side of breast cancer disparities: Links to African ancestry and immunologic tumor responses
Melissa B Davis
Weill Cornell Medicine, New York, NY, United States
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Genomic and epigenomic studies of cholangiocarcinoma in diverse populations
Bin Tean Teh
National Cancer Centre Singapore, Singapore, Singapore
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Wrap-up and opportunities for the future
Lisa A Newman
Weill Cornell Medicine, New York, NY, United States
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Introduction
Padmanee Sharma
UT MD Anderson Cancer Ctr., Houston, TX, United States
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T-cell therapy targeting unique cancer mutations
Steven A Rosenberg
National Cancer Inst., Bethesda, MD, United States
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Redirecting T cells for cancer immunotherapy using next-generation bispecific antibodies and fusion proteins
Pablo Umana
Roche Innovation Center Zurich, Zurich, Switzerland
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Taming the beast: Strategies to target the immune-suppressive macrophage to enhance cancer immune therapy
Judith A Varner
UCSD Moores Cancer Ctr., La Jolla, CA, United States
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Mismatch repair deficiency: A connection between the immune system and cancer genetics
Dung T Le
Johns Hopkins Sidney Kimmel Comp. Cancer Ctr., Baltimore, MD, United States
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Wrap-up and opportunities for the future
Padmanee Sharma
UT MD Anderson Cancer Ctr., Houston, TX, United States
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The evolving landscape of biomarker selection in immunotherapy treatment decisions
Leena Gandhi
Lilly Oncology, Boston, MA, United States
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Predicting immunotherapy response with protein-based tools: PD-L1 and beyond
David L. Rimm
Yale Univ. School of Medicine, New Haven, CT, United States
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Cancer immunoediting: Framing response and resistance in immunotherapy
Gavin P. Dunn
Washington Univ. School of Medicine, Saint Louis, MO, United States
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Improving precision immuno-oncology using novel technologies
David A. Barbie
Dana-Farber Cancer Inst., Boston, MA, United States
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Cancer therapeutics: A view from the microbiota
Christian Jobin
Univ. of Florida, Gainesville, FL, United States
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Dynamic monitoring of the dysbiotic microbiome
Jonathan Braun
Mt. Sinai Medical Center, Los Angeles, CA, United States
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Identification and targeting microbial vulnerabilities
Ami S Bhatt
Stanford Medical School, Stanford, CA, United States
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Encapsulated fecal transplant: It's not just for Clostridium difficile any more!
Elizabeth L Hohmann
Massachusetts General Hospital, Boston, MA, United States
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Delineating human breast tissue architecture with single cell genomics
Nicholas E Navin
UT MD Anderson Cancer Ctr., Bellaire, TX, United States
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Single-cell lineage tracing dissects cellular states and plasticity in glioblastoma
Mario L Suvà
Massachusetts General Hospital, Charlestown, MA, United States
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Multi-dimensional single cell analysis of the tumour microenvironment
Alexander Swarbrick
Garvan Inst. of Medical Research, Darlinghurst, Australia
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Single-cell and spatial gene expression analysis of tumorigenesis
Itai Yanai
NYU Langone Health, New York, NY, United States