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Introduction
Padmanee Sharma
UT MD Anderson Cancer Ctr., Houston, TX, United States
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T-cell therapy targeting unique cancer mutations
Steven A Rosenberg
National Cancer Inst., Bethesda, MD, United States
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Redirecting T cells for cancer immunotherapy using next-generation bispecific antibodies and fusion proteins
Pablo Umana
Roche Innovation Center Zurich, Zurich, Switzerland
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Taming the beast: Strategies to target the immune-suppressive macrophage to enhance cancer immune therapy
Judith A Varner
UCSD Moores Cancer Ctr., La Jolla, CA, United States
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Mismatch repair deficiency: A connection between the immune system and cancer genetics
Dung T Le
Johns Hopkins Sidney Kimmel Comp. Cancer Ctr., Baltimore, MD, United States
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Wrap-up and opportunities for the future
Padmanee Sharma
UT MD Anderson Cancer Ctr., Houston, TX, United States
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The evolving landscape of biomarker selection in immunotherapy treatment decisions
Leena Gandhi
Lilly Oncology, Boston, MA, United States
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Predicting immunotherapy response with protein-based tools: PD-L1 and beyond
David L. Rimm
Yale Univ. School of Medicine, New Haven, CT, United States
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Cancer immunoediting: Framing response and resistance in immunotherapy
Gavin P. Dunn
Washington Univ. School of Medicine, Saint Louis, MO, United States
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Improving precision immuno-oncology using novel technologies
David A. Barbie
Dana-Farber Cancer Inst., Boston, MA, United States
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Cancer therapeutics: A view from the microbiota
Christian Jobin
Univ. of Florida, Gainesville, FL, United States
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Dynamic monitoring of the dysbiotic microbiome
Jonathan Braun
Mt. Sinai Medical Center, Los Angeles, CA, United States
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Identification and targeting microbial vulnerabilities
Ami S Bhatt
Stanford Medical School, Stanford, CA, United States
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Encapsulated fecal transplant: It's not just for Clostridium difficile any more!
Elizabeth L Hohmann
Massachusetts General Hospital, Boston, MA, United States
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Discovery of BLU-667 for RET driven cancers
Jason Brubaker
Blueprint Medicines, Cambridge, MA, United States
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Discovery and development of USP7 inhibitors
Tim Harrison
Almac Discovery, Belfast, Ireland
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Identification and optimization of chemical series that lead to discovery of erdafitinib: A potent pan-fibroblast growth factor receptor (FGFR) inhibitor
Patrick Angibaud
Janssen R & D, Val-de-Reuil, France
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Development of potent and selective CD73 inhibitors: Discovery and characterization of AB680
Jenna Jeffrey
Arcus Biosciences, Inc., Hayward, CA, United States
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How to develop trial objectives: Translation of science from bench to bedside to bench
Patricia M LoRusso
Yale Cancer Center, New Haven, CT, United States
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Modernizing eligibility criteria for oncology clinical trials
Tatiana Prowell
U.S. Food and Drug Administration and Johns Hopkins Kimmel Cancer Center, Silver Spring, MD, United States
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Biostatistical principals of clinical trial design
Mithat Gonen
Mem. Sloan Kettering Cancer Ctr., New York, NY, United States
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Designing meaningful and impactful clinical trials
Jyoti D Patel
Univ. of Chicago Medical Ctr., Chicago, IL, United States
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The changing landscape of oncology drug development
David S Hong
UT MD Anderson Cancer Ctr., Houston, TX, United States
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GO/NO GO decisions in cancer drug discovery: Has the decision making process evolved?
Nancy E. Kohl
Consultant, Wellesley, MA, United States
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Insights from a clinical development prediction algorithm: What we measure matters
David Feltquate
Bristol-Myers Squibb, New York, NY, United States