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Key questions for ctDNA analysis
Paul T Spellman
Oregon Health Science Univ., Portland, OR, United States
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Title to be announced
Jamie Platt
Inivata, Research Triangle Park, NC, United States
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The dual roles of analytical and clinical data in ctDNA test validation
Justin Odegaard
Guardant Health Inc., Redwood City, CA, United States
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Analytical validation of liquid biopsy assays: current challenges and opportunities
Mark Sausen
Personal Genome Diagnostics, Baltimore, MD, United States
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Using large-scale mutagenesis to define cancer risk and understand inhibitor resistance
Douglas Fowler
University of Washington, Seattle, WA, United States
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Escaping the confines of clinical genomics through massively-parallel variant phenotyping
Cory Matthew Johannessen
Broad Inst. of MIT and Harvard, Cambridge, MA, United States
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Multiplexed functional assays to assess BRCA1 variants
Lea Starita
University of Washington, Seattle, WA, United States
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CHASM plus reveals the scope of somatic missense mutations driving human cancers
Rachel Karchin
Johns Hopkins Univ., Baltimore, MD, United States
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Introduction
Massimo Loda
Cornell Univ., Ithaca, NY, United States
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Pathology for cancer researchers: An overview
Jiaoti Huang
Duke Univ. School of Medicine, Durham, NC, United States
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Antibody validation of immunohistochemistry (IHC) and in situ hybridization assays in tissue: Pitfalls, tips, and techniques
Angelo M De Marzo
John Hopkins Univ. School of Medicine, Baltimore, MD, United States
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Molecular pathology and diagnostics
Andrea L Richardson
Johns Hopkins Univ. School of Medicine, Washington, DC, United States
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Computational pathology, imaging, and artificial intelligence
Andrew H Beck
PathAI, Cambridge, MA, United States
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Tracking the arc of leukemia development from the beginning to the end
John E Dick
Univ. of Toronto, Toronto, ON, Canada
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Quantifying clonal dynamics through treatment and metastasis
Christina Curtis
Stanford University, Stanford, CA, United States
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Reconstructing the life history of cancers
Moritz Gerstung
European Bioinformatics Institute, Hinxton, Cambridgeshire, United Kingdom
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Evolution and heterogeneity in glioblastomas
Raul Rabadan
Columbia Univ. Medical Ctr., New York, NY, United States
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From discovery to clinics: Design considerations in biomarker studies
Yingye Zheng
Fred Hutchinson Cancer Research Ctr., Seattle, WA, United States
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Needle in a haystack: Biomarker discovery in high-dimensional data
Shilin Zhao
Vanderbilt University Medical Center, Nashville, TN, United States
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Precision oncology: Integrating biomarkers in phase III clinical trial designs
Antje Hoering
Cancer Research and Biostatistics, Seattle, WA, United States
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Population risk stratification: Integrating biomarkers in cancer risk assessment
Ruth Pfeiffer
NCI-DCEG, Bethesda, MD, United States
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Delineating human breast tissue architecture with single cell genomics
Nicholas E Navin
UT MD Anderson Cancer Ctr., Bellaire, TX, United States
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Single-cell lineage tracing dissects cellular states and plasticity in glioblastoma
Mario L Suvà
Massachusetts General Hospital, Charlestown, MA, United States
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Multi-dimensional single cell analysis of the tumour microenvironment
Alexander Swarbrick
Garvan Inst. of Medical Research, Darlinghurst, Australia
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Single-cell and spatial gene expression analysis of tumorigenesis
Itai Yanai
NYU Langone Health, New York, NY, United States