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Opening Video
Charles L. Sawyers
Memorial Sloan-Kettering Cancer Center, New York, NY, United States
Trailer for Cancer: The Emperor of All Maladies
Ken Burns
Florentine Films
Opening Remarks
Margaret Foti
American Association for Cancer Research, Philadelphia, PA
President's Remarks
Charles L. Sawyers
Memorial Sloan-Kettering Cancer Center, New York, NY, United States
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Eighth Annual AACR Team Science Award Presentation
The Duke, Hopkins, National Cancer Institute Malignant Brain Tumor Team
Duke University Medical Center, Durham, NC; John Hopkins Kimmel Comprehensive Cancer Center, Baltimore, MD; and National Cancer Institute, Bethesda, MD
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Eleventh Annual AACR Award for Lifetime Achievement in Cancer Research Presentation
Douglas Hanahan
Swiss Cancer Center Lausanne, Lausanne, Switzerland
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Recognition of the Fellows of the AACR Academy
Margaret Foti
American Association for Cancer Research, Philadelphia, PA
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2014 AACR Distinguished Public Service Award Presentation
Charles L. Sawyers
Memorial Sloan-Kettering Cancer Center, New York, NY, United States
Award Recipient (Video)
U.S. Senator Dick Durbin [D-IL]
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Young Champion in Cancer Research Award Presentation
Charles L. Sawyers
Memorial Sloan-Kettering Cancer Center, New York, NY, United States
Award Recipient
Elana Simon
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Eighth Annual AACR Margaret Foti Award for Leadership and Extraordinary Achievements in Cancer Research Presentation
Joan S. Brugge
Harvard Medical School, Boston, MA
Award Recipient
Webster K. Cavenee
University of California at San Diego, La Jolla, CA
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New targets on the KRAS pathway
Frank McCormick
UCSF Helen Diller Family Comp. Cancer Ctr., San Francisco, CA, United States
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Transcriptional and epigenetic control of tumor cells
Richard A. Young
MIT Whitehead Inst. for Biomed. Research, Cambridge, MA, United States
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The two faces of p53: Tumor suppressor and oncogene
Carol L. Prives
Columbia Univ., New York, NY, United States
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Final results of a randomized Phase II study of PD 0332991, a cyclin-dependent kinase (CDK)-4/6 inhibitor, in combination with letrozole vs letrozole alone for first-line treatment of ER+/HER2- advanced breast cancer (PALOMA-1; TRIO-18)
Richard S. Finn
UCLA, Los Angeles, CA, United States
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Discussant
José Baselga
Mem. Sloan-Kettering Cancer Ctr., New York, NY, United States
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New lymphoma therapies based on functional and structural genomics
Louis M. Staudt
NCI-CCR, Bethesda, MD, United States
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Diet and cancer: Status report in 2014
Walter C. Willett
Harvard School of Public Health, Boston, MA, United States
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Tumor-specific immune activation: Immuno-oncology comes of age
Roger M. Perlmutter
Merck Research Laboratories, Rahway., NJ, United States
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- Unknown permission
for presentation
Chairperson
Joseph Paul Eder
Yale University, New Haven, CT, United States
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Efficacy and toxicity management of 19-28z CAR T cell therapy in B cell acute lymphoblastic leukemia
Renier Brentjens
Mem. Sloan-Kettering Cancer Ctr., New York, NY, United States
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- Coming soon
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Discussant
Carl H. June
Abramson Cancer Ctr. of Univ. of Penn., Philadelphia, PA, United States
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Clinical safety and activity in a phase I trial of AG-221, a first in class, potent inhibitor of the IDH2-mutant protein, in patients with IDH2 mutant positive advanced hematologic malignancies
Eytan Stein
Memorial Sloan-Kettering Cancer Center, New York, NY, United States
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Discussant
John C. Byrd
Ohio State Univ. Comp. Cancer Ctr., Columbus, OH, United States
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Antitumor activity of the anti-PD-1 monoclonal antibody MK-3475 in melanoma(MEL): Correlation of tumor PD-L1 expression with outcome
Adil I. Daud
UCSF School of Medicine, San Francisco, CA, United States
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MK-3475 (anti-PD-1 monoclonal antibody) for non-small cell lung cancer (NSCLC): Antitumor activity and association with tumor PD-L1 expression
Leena Gandhi
Dana-Farber Cancer Institute, Boston, MA, United States
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Engineering T cells for cancer: CARs in the clinic
Carl H. June
Abramson Cancer Ctr. of Univ. of Penn., Philadelphia, PA, United States
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Investigating inhibition of the CD47 "don't eat me" signal to enable tumor phagocytic removal and augmented cross presentation to T cells
Irving L. Weissman
Stanford Univ. School of Medicine, Stanford, CA, United States
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The curative potential of T cell transfer therapy for patients with cancer
Steven A. Rosenberg
National Cancer Inst., Bethesda, MD, United States