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Introduction
Padmanee Sharma
UT MD Anderson Cancer Ctr., Houston, TX, United States
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T-cell therapy targeting unique cancer mutations
Steven A Rosenberg
National Cancer Inst., Bethesda, MD, United States
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- Unknown permission
for presentation
Redirecting T cells for cancer immunotherapy using next-generation bispecific antibodies and fusion proteins
Pablo Umana
Roche Innovation Center Zurich, Zurich, Switzerland
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Taming the beast: Strategies to target the immune-suppressive macrophage to enhance cancer immune therapy
Judith A Varner
UCSD Moores Cancer Ctr., La Jolla, CA, United States
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- Some slides withheld
Mismatch repair deficiency: A connection between the immune system and cancer genetics
Dung T Le
Johns Hopkins Sidney Kimmel Comp. Cancer Ctr., Baltimore, MD, United States
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Wrap-up and opportunities for the future
Padmanee Sharma
UT MD Anderson Cancer Ctr., Houston, TX, United States
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Introduction
Silvia C Formenti
Weill Cornell Medical College, New York, NY, United States
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Neoadjuvant immuno-radiotherapy (NIRT) in head and neck cancer: Phase I/Ib study of combined PD-1/SBRT prior to surgical resection
Rom Leidner
EACRI - Providence Cancer Center, Portland, OR, United States
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Discussant
Christine H Chung
Moffitt Cancer Center, Tampa, FL, United States
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Phase (Ph) I/II study of MBG453± spartalizumab (PDR001) in patients (pts) with advanced malignancies
Giuseppe Curigliano
Istituto Europeo di Oncologia IRCCS, Milan, Italy
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Discussant
David S Hong
UT MD Anderson Cancer Ctr., Houston, TX, United States
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Gilteritinib significantly prolongs overall survival in patients with FLT3-mutated (FLT3mut+) relapsed/refractory (R/R) acute myeloid leukemia (AML): Results from the Phase III ADMIRAL trial
Alexander E Perl
Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, United States
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Discussant
Tapan M. Kadia
UT MD Anderson Cancer Ctr., Houston, TX, United States
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Phase I dose-escalation study of endoscopic intratumoral injection of OBP-301 (telomelysin) with radiotherapy in esophageal cancer patients unfit for standard treatments
Toshiyoshi Fujiwara
Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
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Geoffrey Y Ku
Memorial Sloan Kettering Cancer Center, New York, NY, United States
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A journey from phosphotyrosine to phosphohistidine with unexpected links to pancreatic cancer and liver cancer along the way
Tony Hunter
Salk Institute, La Jolla, CA, United States
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A-to-I RNA editing in cancer
Erez Y Levanon
Bar-Ilan University, Ramat-Gan, Israel
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Defining and targeting malignant brain tumor hierarchies
Peter B Dirks
The Hospital for Sick Children, Toronto, ON, Canada
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Overcoming resistance to antibody-targeted cancer immunotherapy
Louis M Weiner
Georgetown Lombardi Comp. Cancer Ctr., Washington, DC, United States
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Engaging and involving patients in translational cancer research
Bodour Salhia
University of Southern California, Los Angeles, CA, United States
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New single-cell methods for oncology and immuno-oncology
James R Heath
California Inst. of Technology, Pasadena, CA, United States
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Next-generation characterization and functional mapping of the cancer cell line encyclopedia: Implications for targeting dysregulated metabolism in cancer
William R. Sellers
Broad Institute, Cambridge, MA, United States
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Novel therapeutic strategies in multiple myeloma
Kenneth C Anderson
Dana-Farber Cancer Inst., Boston, MA, United States
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Obesity: Changing the landscape for cancer risk in populations
Elizabeth A Platz
Johns Hopkins School of Public Health, Baltimore, MD, United States
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Prostate cancer health disparity
Timothy R Rebbeck
Harvard School of Public Health, Boston, MA, United States