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Pan-cancer Genomic Analysis
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Introduction
Gad Getz
MGH Cancer Center & Dept of Pathology, Charlestown, MA, United States
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Invited Speaker
Lincoln Stein
Ontario Institute for Cancer Research, Toronto, ON, Canada
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Pan-cancer study of recurrent and heterogeneous RNA aberrations and association with whole-genome variants
Angela Norie Brooks
UC Santa Cruz, Santa Cruz, CA, United States
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The genetic archeology of 2,663 cancers
Peter Van Loo
The Francis Crick Institute, London, United Kingdom
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Pan-cancer driver discovery
Gad Getz
MGH Cancer Center & Dept of Pathology, Charlestown, MA, United States
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Introduction: AACR Project GENIE
Charles L. Sawyers
Mem. Sloan Kettering Cancer Ctr., New York, NY, United States
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Landscape analysis of the initial data release from AACR Project GENIE
Ethan Cerami
Dana-Farber Cancer Inst., Boston, MA, United States
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Landscape of somatic ERBB2 Mutations: Findings from AACR GENIE and comparison to ongoing ERBB2 mutant basket study
Alison Schram
Memorial Sloan Kettering Cancer Center, New York, NY, United States
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Clinical actionability and clinical trial matching for GENIE patient genotypes using My Cancer Genome, Personalized Cancer Therapy, and OncoKB
Christine M Micheel
Vanderbilt-Ingram Cancer Center, Nashville, TN, United States
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Characterization of total mutational burden in the GENIE cohort: Small and large panels can provide TMB information but to varying degrees
Alexander S Baras
Johns Hopkins Hospital, Baltimore, MD, United States
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Panel Discussion
Charles L. Sawyers
Mem. Sloan Kettering Cancer Ctr., New York, NY, United States
Ethan Cerami
Dana-Farber Cancer Inst., Boston, MA, United States
Alison Schram
Memorial Sloan Kettering Cancer Center, New York, NY, United States
Christine M Micheel
Vanderbilt-Ingram Cancer Center, Nashville, TN, United States
Alexander S Baras
Johns Hopkins Hospital, Baltimore, MD, United States
Lincoln Stein
Ontario Institute for Cancer Research, Toronto, ON, Canada
Angela Norie Brooks
UC Santa Cruz, Santa Cruz, CA, United States
Peter Van Loo
The Francis Crick Institute, London, United Kingdom
Gad Getz
MGH Cancer Center & Dept of Pathology, Charlestown, MA, United States