Search:

Search for text in:

separate each search
term with a space

Multiple terms:

Additional Search Filters:

clear all | select all

Conference Years:

clear all | select all

Days Within Meeting:

clear all | select all

Conferences:

Availability:

clear all | select all

Participation Type:

clear all | select all

Topic Tracks*:

clear all | select all

Organ Site Tracks*:

Showing session: reset

Next-Generation Small Molecules: From Hits to Leads to Candidates

  • Sort by:
  • Browse by:
<< first | < prev page: of 1 records per page: next > | last >>
pages: 1 presentations: 1 to 7 of 7
Next-Generation Small Molecules: From Hits to Leads to Candidates
Evaluation of the therapeutic potential of phosphine oxide pyrazole inhibitors in tumors harboring EGFR C797S mutation
Nicolas Floch
AstraZeneca, Cambridge, United Kingdom
from AACR Annual Meeting 2019 on April 2, 2019 3:00 PM-5:00 PM
Next-Generation Small Molecules: From Hits to Leads to Candidates
GNE-0011, a novel monovalent BRD4 degrader
Robert A Blake
Genentech, Inc., South San Francisco, CA, United States
from AACR Annual Meeting 2019 on April 2, 2019 3:00 PM-5:00 PM
Next-Generation Small Molecules: From Hits to Leads to Candidates
Novel, potent, and selective small-molecule inhibitors modulating immuno-oncology targets CD73, A2A/A2B adenosine receptors and CSF1R discovered via DNA-encoded library screening
Andrew J McRiner
X-Chem Pharmaceuticals, Waltham, MA, United States
from AACR Annual Meeting 2019 on April 2, 2019 3:00 PM-5:00 PM
Next-Generation Small Molecules: From Hits to Leads to Candidates
Identification of BAY-218, a potent and selective small-molecule AhR inhibitor, as a new modality to counteract tumor immunosuppression
Ingo Volker Hartung
Bayer AG, Pharmaceuticals Division, Berlin, Germany
from AACR Annual Meeting 2019 on April 2, 2019 3:00 PM-5:00 PM
Next-Generation Small Molecules: From Hits to Leads to Candidates
  •  
  • Permission not
    granted for presentation
  •  
  •  
Discovery of AMG 510, a first-in-human covalent inhibitor of KRASG12C for the treatment of solid tumors
Brian A Lanman
Amgen, Inc., Thousand Oaks, CA, United States
from AACR Annual Meeting 2019 on April 2, 2019 3:00 PM-5:00 PM
Next-Generation Small Molecules: From Hits to Leads to Candidates
Discovery of E7766: A representative of a novel class of macrocycle-bridged STING agonists (MBSAs) with superior potency and pan-genotypic activity
Dae-Shik Kim
Eisai Inc., Andover, MA, United States
from AACR Annual Meeting 2019 on April 2, 2019 3:00 PM-5:00 PM
Next-Generation Small Molecules: From Hits to Leads to Candidates
Open science medicinal chemistry: Towards a treatment for DIPG
Sue Cramp
Charles River Early Discovery, Harlow, United Kingdom
from AACR Annual Meeting 2019 on April 2, 2019 3:00 PM-5:00 PM
<< first | < prev page: of 1 records per page: next > | last >>
pages: 1 presentations: 1 to 7 of 7